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Rapid and Easy Technique for Improving In Vitro Dissolution of a BCS Class II Compound – 2010

Released By Thermo Fisher Scientific Pharma Services

The purpose of this study was to evaluate the use of the hot melt granulation technique for improving dissolution and bioavailability of a poorly soluble API. Coating was achieved by adjusting the spray rate and inlet temperatures. The final formulation was found to be stable.

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